BDBM50090067 6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL6742

SMILES: CC1(C)N=C(N)N=C(N)N1c1ccccc1

InChI Key: InChIKey=VMVKLCXTXSSZSI-UHFFFAOYSA-N

Data: 12 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50090067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Human)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Lactobacillus casei)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (malaria parasite P. falciparum)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Chicken)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		204	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli (strain K12))	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase [A16V,S108T] (malaria parasite P. falciparum)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (Leishmania major)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Lactobacillus casei)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.09E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase type 1 (Escherichia coli)	BDBM50090067 (6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.09E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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