BDBM50091438 (E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-indol-3-yl)-piperidin-1-yl]-pentyl}-acrylamide::(E)-3-(3,4-dichlorophenyl)-N-(5-(4-(5-hydroxy-1H-indol-3-yl)piperidin-1-yl)pentyl)acrylamide::3-(3,4-dichlorophenyl)-N-(5-(4-(5-hydroxy-1H-indol-3-yl)piperidin-1-yl)pentyl)acrylamide::CHEMBL432713::TCMDC-139245
SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1
InChI Key InChIKey=QBRLVMQBZIFWTB-WEVVVXLNSA-N
Data 18 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50091438
Affinity DataKi: 3.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 1F receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Binding affinity for 5-hydroxytryptamine 1E receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Binding affinity for Dopamine receptor D3 was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity for Dopamine receptor D2 was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity for 5-hydroxytryptamine 2A receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity for 5-hydroxytryptamine 2B receptor was determinedMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Antagonist activity at human CCR2 receptorMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Binding affinity of the compound at C-C chemokine receptor type 2 was determinedMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of [125I]-MCP-1 binding to the cloned C-C chemokine receptor type 2B expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Antagonist activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of [125I]MCP-1 binding to the cloned C-C chemokine receptor type 2B expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Binding affinity for 5-hydroxytryptamine 7 receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity for 5-hydroxytryptamine 6 receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity for 5-hydroxytryptamine 2C receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 4.26E+3nMAssay Description:Compound was evaluated for the antagonist activity against C-C chemokine receptor type 5More data for this Ligand-Target Pair