BDBM50091822 8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one::CHEMBL301466
SMILES Clc1cc2NC(=O)C3CNCCN3c2cc1Cl
InChI Key InChIKey=PHGWDAICBXUJDU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50091822
Affinity DataKi: 4nMAssay Description:Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...More data for this Ligand-Target Pair
Affinity DataEC50: 7.30nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by flu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by flu...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...More data for this Ligand-Target Pair