BDBM50093313 3-[3-Oxo-4-(5-piperidin-1-yl-pentyl)-3,4-dihydro-2H-benzo[1,4]oxazin-2-yl]-benzamidine::CHEMBL341187

SMILES NC(=N)c1cccc(c1)C1Oc2ccccc2N(CCCCCN2CCCCC2)C1=O

InChI Key InChIKey=BSUGZKLIRUEXFN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093313   

TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093313(3-[3-Oxo-4-(5-piperidin-1-yl-pentyl)-3,4-dihydro-2...)
Affinity DataIC50: 53nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093313(3-[3-Oxo-4-(5-piperidin-1-yl-pentyl)-3,4-dihydro-2...)
Affinity DataIC50: 990nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093313(3-[3-Oxo-4-(5-piperidin-1-yl-pentyl)-3,4-dihydro-2...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093313(3-[3-Oxo-4-(5-piperidin-1-yl-pentyl)-3,4-dihydro-2...)
Affinity DataIC50: 2.10E+4nMAssay Description:Compound was tested for in vitro inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed