BDBM50094189 17-Aziridin-2-ylmethyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one::CHEMBL138580

SMILES CC12CCC3C(CC=C4CC(=O)CCC34C)C1CCC2CC1CN1

InChI Key InChIKey=MFWABCGQFDBVQU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50094189   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094189(17-Aziridin-2-ylmethyl-10,13-dimethyl-1,2,4,7,8,9,...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of steroid 5-alpha-reductase type II isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094189(17-Aziridin-2-ylmethyl-10,13-dimethyl-1,2,4,7,8,9,...)
Affinity DataIC50:  1.32E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094189(17-Aziridin-2-ylmethyl-10,13-dimethyl-1,2,4,7,8,9,...)
Affinity DataIC50:  1.80E+3nMAssay Description:Tested for inhibitory activity against Cytochrome P450 17 from human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50094189(17-Aziridin-2-ylmethyl-10,13-dimethyl-1,2,4,7,8,9,...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of steroid 5-alpha-reductase type I isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed