BDBM50094941 CHEMBL3589285

SMILES CN1CCCc2c1cc([nH]c2=O)-c1ccc(Br)cc1

InChI Key InChIKey=FASROOIKQQJQSJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50094941   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50094941(CHEMBL3589285)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human TNKS2 (873 to 1162 residues) measured after 15 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50094941(CHEMBL3589285)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human TNKS1 catalytic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50094941(CHEMBL3589285)
Affinity DataIC50: 423nMAssay Description:Inhibition of human TNKS2 catalytic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50094941(CHEMBL3589285)
Affinity DataIC50: 423nMAssay Description:Inhibition of human TNKS1 (1030 to 1317 residues) measured after 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50094941(CHEMBL3589285)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50094941(CHEMBL3589285)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant PARP1 incubated for 30 mins in the presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed