BDBM50095474 CHEMBL3590478::US10329294, Example 2
SMILES Cn1cc(NC(=O)c2cnn3ccc(N[C@@H]4CCCC[C@@H]4N)nc23)c(n1)C(F)(F)F
InChI Key InChIKey=KMUHJPGOMYFEPW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50095474
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human IRAK4 assessed as phosphorylation of fluorescent peptide substrate after 30 mins by fluorescent polarization readerMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of IRAK4 in human PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair