BindingDB logo
myBDB logout

BDBM50097891 4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole::CHEMBL352186

SMILES: COc1ccc2[nH]cc(CCN3CCCC3)c2c1F

InChI Key: InChIKey=FJCRAYWNOXUYOO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097891   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50097891
PNG
(4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...)
Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F
Show InChI InChI=1S/C15H19FN2O/c1-19-13-5-4-12-14(15(13)16)11(10-17-12)6-9-18-7-2-3-8-18/h4-5,10,17H,2-3,6-9H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.120n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinitty towards human 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT-as radioligand


Bioorg Med Chem Lett 11: 793-5 (2001)


Article DOI: 10.1016/s0960-894x(01)00062-2
BindingDB Entry DOI: 10.7270/Q2ZC824R
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50097891
PNG
(4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...)
Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F
Show InChI InChI=1S/C15H19FN2O/c1-19-13-5-4-12-14(15(13)16)11(10-17-12)6-9-18-7-2-3-8-18/h4-5,10,17H,2-3,6-9H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
130n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinitty towards rat 5-hydroxytryptamine 2A receptor was determined using [125I]- DOI as radioligand


Bioorg Med Chem Lett 11: 793-5 (2001)


Article DOI: 10.1016/s0960-894x(01)00062-2
BindingDB Entry DOI: 10.7270/Q2ZC824R
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50097891
PNG
(4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...)
Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F
Show InChI InChI=1S/C15H19FN2O/c1-19-13-5-4-12-14(15(13)16)11(10-17-12)6-9-18-7-2-3-8-18/h4-5,10,17H,2-3,6-9H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
140n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinitty towards rat 5-hydroxytryptamine 2C receptor was determined using [125I]- DOI as radioligand


Bioorg Med Chem Lett 11: 793-5 (2001)


Article DOI: 10.1016/s0960-894x(01)00062-2
BindingDB Entry DOI: 10.7270/Q2ZC824R
More data for this
Ligand-Target Pair