BDBM50098495 4-Chloro-6-ethyl-thieno[2,3-d]pyrimidine::CHEMBL269056

SMILES CCc1cc2c(Cl)ncnc2s1

InChI Key InChIKey=IYTRSBKGPIDYHI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098495   

TargetVascular cell adhesion protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098495BDBM50098495(4-Chloro-6-ethyl-thieno[2,3-d]pyrimidine | CHEMBL2...)
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro potency against TNF alpha induced expression of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098495BDBM50098495(4-Chloro-6-ethyl-thieno[2,3-d]pyrimidine | CHEMBL2...)
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098495BDBM50098495(4-Chloro-6-ethyl-thieno[2,3-d]pyrimidine | CHEMBL2...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro potency against TNF alpha induced expression of intercellular adhesion molecule-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed