BDBM50098597 CHEMBL3594312

SMILES CC(C)(C)S(=O)(=O)c1ccc2NC(=O)CCCc3ccc(cc3)C(Nc3ccc4c(N)nccc4c3)C(=O)NCc1c2

InChI Key InChIKey=ZOWREHOVFWKKPQ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50098597   

TargetKallikrein-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098597(CHEMBL3594312)
Affinity DataKi:  22nMAssay Description:Inhibition of human tissue kallikrein 1 measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098597(CHEMBL3594312)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant TF/F7a complex using S2288 as substrate preincubated for 15 mins followed by protein addition measured for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098597(CHEMBL3594312)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of human F10a using S2222 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098597(CHEMBL3594312)
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human plasma kallikrein using S2302 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098597(CHEMBL3594312)
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human trypsin measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098597(CHEMBL3594312)
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of human thrombin using S2238 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098597(CHEMBL3594312)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human APC measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098597(CHEMBL3594312)
Affinity DataKi: >3.50E+4nMAssay Description:Inhibition of human F9a measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed