BDBM50099204 1229U91::CHEMBL409762::GR-231118::Ile-Glu-Pro-Dpr-Tyr-Arg-Leu-Arg-Tyr-NH2Ile-Glu-Pro-Dpr-Tyr-Arg-Leu-Arg-Tyr-NH2

SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H]1CCC(=O)NC[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCC(=O)NC[C@H](NC(=O)[C@@H]2CCCN2C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](N)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=RJRBRCCJETZJLT-VHUVHYDGSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099204   

TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50099204(1229U91 | CHEMBL409762 | GR-231118 | Ile-Glu-Pro-D...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]18 from human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50099204(1229U91 | CHEMBL409762 | GR-231118 | Ile-Glu-Pro-D...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H](2R,7R)-10 from human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins in presence of sodium-free HE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(RAT)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50099204(1229U91 | CHEMBL409762 | GR-231118 | Ile-Glu-Pro-D...)
Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50099204(1229U91 | CHEMBL409762 | GR-231118 | Ile-Glu-Pro-D...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human NPY Y4 receptor expressed in HEK293 cells co-expressing CRE-Luc gene assessed as inhibition of forskolin stimulated lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50099204(1229U91 | CHEMBL409762 | GR-231118 | Ile-Glu-Pro-D...)
Affinity DataEC50:  8.5nMAssay Description:Agonist activity at human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as induction of calcium mobilization by aequorin l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed