BDBM50099792 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclobutyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL50517

SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1CCC1

InChI Key InChIKey=AFSSAOBKLVREBP-OAHLLOKOSA-N

Data  3 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099792   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50099792(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1...)
Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1CCC1
Show InChI InChI=1S/C21H25BrN2O2/c1-26-20-17-10-3-2-9-16(17)19(22)12-18(20)21(25)23-13-15-8-5-11-24(15)14-6-4-7-14/h2-3,9-10,12,14-15H,4-8,11,13H2,1H3,(H,23,25)/t15-/m1/s1
Affinity DataKi:  48nMAssay Description:Binding affinity for sigma-1 receptor measured on guinea pig brain membranes using [3H]-(+)-pentazocine as radioligand.More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50099792(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1...)
Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1CCC1
Show InChI InChI=1S/C21H25BrN2O2/c1-26-20-17-10-3-2-9-16(17)19(22)12-18(20)21(25)23-13-15-8-5-11-24(15)14-6-4-7-14/h2-3,9-10,12,14-15H,4-8,11,13H2,1H3,(H,23,25)/t15-/m1/s1
Affinity DataKi:  90nMAssay Description:Binding affinity for dopamine receptor D3 expressed in Sf9 cells using [125I]-IABN the radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50099792(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1...)
Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1CCC1
Show InChI InChI=1S/C21H25BrN2O2/c1-26-20-17-10-3-2-9-16(17)19(22)12-18(20)21(25)23-13-15-8-5-11-24(15)14-6-4-7-14/h2-3,9-10,12,14-15H,4-8,11,13H2,1H3,(H,23,25)/t15-/m1/s1
Affinity DataKi:  277nMAssay Description:Binding affinity for dopamine receptor D2 long expressed in Sf9 cells using [125I]-IABN radioligand.More data for this Ligand-Target Pair