BDBM50099911 4-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL31967

SMILES CSc1sc(cc1-c1nc(cs1)-c1ccc2OCOc2c1)C(N)=N

InChI Key InChIKey=ONJMNFUCIIFBMG-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099911   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099911(4-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-5-methyls...)
Affinity DataKi:  91nMAssay Description:Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099911(4-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-5-methyls...)
Affinity DataKi:  880nMAssay Description:Inhibitory activity of the compound against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099911(4-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-5-methyls...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory activity of the compound against tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099911(4-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-5-methyls...)
Affinity DataKi:  1.08E+4nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099911(4-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-5-methyls...)
Affinity DataKi: >2.90E+4nMAssay Description:Inhibitory activity of the compound against Thrombin (no observable inhibition at this screening concentration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed