BDBM50100284 2-(2,4-Dichloro-benzenesulfonyl)-4-imidazol-1-ylmethyl-benzonitrile::CHEMBL22238

SMILES Clc1ccc(c(Cl)c1)S(=O)(=O)c1cc(Cn2ccnc2)ccc1C#N

InChI Key InChIKey=JGDWEVDLNONADN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100284   

LigandChemical structure of BindingDB Monomer ID 50100284BDBM50100284(2-(2,4-Dichloro-benzenesulfonyl)-4-imidazol-1-ylme...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50100284BDBM50100284(2-(2,4-Dichloro-benzenesulfonyl)-4-imidazol-1-ylme...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed