BDBM50100588 6-(4-tert-Butyl-phenyl)-7-(4-dimethylamino-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine::CHEMBL66568

SMILES CN(C)c1ccc(cc1)-c1nc2ncnc(N)c2cc1-c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=LZNSOVAHFMAUKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100588   

TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100588(6-(4-tert-Butyl-phenyl)-7-(4-dimethylamino-phenyl)...)
Affinity DataIC50:  62.5nMAssay Description:In vitro inhibition of Adenosine kinase (AK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100588(6-(4-tert-Butyl-phenyl)-7-(4-dimethylamino-phenyl)...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of adenosine phosphorylation in confluent IMR-32 (human neuroblastoma) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed