BDBM50101873 2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-carboxamidine::2-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-6-BROMO-4-METHYLBENZENOLATE::CHEMBL48608

SMILES Cc1cc(Br)c(O)c(c1)-c1cc2cc(ccc2[nH]1)C(N)=N

InChI Key InChIKey=BVTBOJXEAPSOEB-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50101873   

TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  52nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  55nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  100nMAssay Description:Inhibitory activity against Coagulation factor X in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  110nMAssay Description:Inhibitory activity against urokinase-type plasminogen activator (microPa) in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  180nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  320nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  360nMAssay Description:Inhibitory activity against thrombin(fIIa) in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  460nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  600nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  640nMAssay Description:Inhibitory activity against trypsin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101873(2-(3-Bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibitory activity against plasmin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed