BDBM50102781 2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine::CHEMBL330460

SMILES CCN(CC)c1ccc(-c2nc3ccc(cc3[nH]2)C(N)=N)c(O)c1

InChI Key InChIKey=WCAHISANJALHOR-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102781   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102781(2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidaz...)
Affinity DataKi:  1.30E+4nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102781(2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidaz...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102781(2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidaz...)
Affinity DataKi:  2.50E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102781(2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidaz...)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102781(2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidaz...)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102781(2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidaz...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed