BDBM50103342 4-(5-{[Benzyl-(1-benzyl-2-oxo-pyrrolidin-3-yl)-amino]-methyl}-imidazol-1-ylmethyl)-benzonitrile::CHEMBL101708

SMILES O=C1[C@H](CCN1Cc1ccccc1)N(Cc1cncn1Cc1ccc(cc1)C#N)Cc1ccccc1

InChI Key InChIKey=GCCKPAUGIAPVNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103342   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103342(4-(5-{[Benzyl-(1-benzyl-2-oxo-pyrrolidin-3-yl)-ami...)
Affinity DataIC50: 67nMAssay Description:In vitro inhibition of farnesyl transferase using purified recombinant human enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50103342(4-(5-{[Benzyl-(1-benzyl-2-oxo-pyrrolidin-3-yl)-ami...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration of geranylgeranyl-protein transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed