BDBM50105753 4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-imidazol-1-yl]-piperidine-1-carboxylic acid ethyl ester::CHEMBL95931::D3RKN_45

SMILES: CCOC(=O)N1CCC(CC1)n1cnc(c1-c1ccnc(N)n1)-c1ccc(F)cc1

InChI Key: InChIKey=WNZMTWAJENZPDM-UHFFFAOYSA-N

Data: 1 IC50  9 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50105753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase JAK2 (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50105753 (4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair