BDBM50108563 Adamantane-1-carboxylic acid (5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-amide::CHEMBL108971
SMILES NS(=O)(=O)c1nnc(NC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)s1
InChI Key InChIKey=NBKDQESIWDNDOT-BQHQMIMCSA-N
Data 19 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50108563
Affinity DataKi: 2.80nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human carbonic anhydrase-2 cytosolic isoform after 15 mins by Stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 118nMAssay Description:Inhibition of human recombinant carbonic anhydrase 13 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 349nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of human recombinant carbonic anhydrase 5b after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: 448nMAssay Description:Inhibition of human recombinant carbonic anhydrase 5a after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 652nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 765nMAssay Description:Inhibition of human recombinant carbonic anhydrase 6 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:Inhibitory effect on human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:Inhibition of human carbonic anhydrase-1 cytosolic isoform after 15 mins by Stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 883nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 3 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+6nMAssay Description:Inhibition of human carbonic anhydrase-3 cytosolic isoform after 15 mins by Stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair