BDBM50108878 1-(3,4-Dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone::1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethanone::CHEMBL160038::NEBICAPONE

SMILES Oc1cc(cc(c1O)[N+]([O-])=O)C(=O)Cc1ccccc1

InChI Key InChIKey=MRFOLGFFTUGAEB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108878   

TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108878(1-(3,4-Dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of Catechol O-methyltransferase activity in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108878(1-(3,4-Dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone...)
Affinity DataIC50:  690nMAssay Description:Inhibitory activity against COMT in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108878(1-(3,4-Dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against COMT in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108878(1-(3,4-Dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone...)
Affinity DataIC50:  6.96E+5nMAssay Description:Inhibition of Catechol O-methyltransferase activity in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed