BDBM50109084 (3-Methoxy-benzyl)-(3-phenyl-isoxazol-5-yl)-(3-piperidin-1-yl-propyl)-amine::CHEMBL108716

SMILES COc1cccc(CN(CCCN2CCCCC2)c2cc(no2)-c2ccccc2)c1

InChI Key InChIKey=NIFMHUZRWOEKJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109084   

TargetProteinase-activated receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109084((3-Methoxy-benzyl)-(3-phenyl-isoxazol-5-yl)-(3-pip...)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonistic activity against thrombin receptor, inhibition of secreted radiolabeled [3H]5-HT from washed human platelets stimulated by 3 uM thrombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109084((3-Methoxy-benzyl)-(3-phenyl-isoxazol-5-yl)-(3-pip...)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonistic activity against thrombin receptor, inhibition of secreted radiolabeled [3H]5-HT from washed human platelets stimulated by 3 uM thrombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed