BDBM50111915 2-(3-(9-chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)phenyl)-N-(3,4,5-trimethoxyphenyl)acetamide::2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(3,4,5-trimethoxy-phenyl)-acetamide::CHEMBL172119::LY-402913

SMILES COc1cc(NC(=O)Cc2cccc(c2)-n2c3cccc(Cl)c3c3noc(C)c3c2=O)cc(OC)c1OC

InChI Key InChIKey=PBHNQPNTZGNYBI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111915   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50111915(2-(3-(9-chloro-3-methyl-4-oxoisoxazolo[4,3-c]quino...)
Affinity DataEC50:  900nMAssay Description:In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50111915(2-(3-(9-chloro-3-methyl-4-oxoisoxazolo[4,3-c]quino...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of MRP1-mediated transport of [3H]LTC4 expressed in human HeLa T5 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed