BDBM50112382 1-(3-Chloro-phenyl)-4-[3-(4'-fluoro-biphenyl-4-ylmethyl)-3H-imidazol-4-ylmethyl]-piperazin-2-one::CHEMBL23490

SMILES: Fc1ccc(cc1)-c1ccc(Cn2cncc2CN2CCN(C(=O)C2)c2cccc(Cl)c2)cc1

InChI Key: InChIKey=XAOIXEKQWGJTAE-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Human)	BDBM50112382 (1-(3-Chloro-phenyl)-4-[3-(4'-fluoro-biphenyl-4-ylm...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bovine)	BDBM50112382 (1-(3-Chloro-phenyl)-4-[3-(4'-fluoro-biphenyl-4-ylm...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bovine)	BDBM50112382 (1-(3-Chloro-phenyl)-4-[3-(4'-fluoro-biphenyl-4-ylm...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair