BDBM50112568 CHEMBL24092::N-tert-Butyl-N'-(3-chloro-4-oxazol-5-yl-phenyl)-oxalamide

SMILES CC(C)(C)NC(=O)C(=O)Nc1ccc(-c2cnco2)c(Cl)c1

InChI Key InChIKey=FWCWLBJSNMKVQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112568   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50112568(CHEMBL24092 | N-tert-Butyl-N'-(3-chloro-4-oxazol-5...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50112568(CHEMBL24092 | N-tert-Butyl-N'-(3-chloro-4-oxazol-5...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50112568(CHEMBL24092 | N-tert-Butyl-N'-(3-chloro-4-oxazol-5...)
Affinity DataIC50:  55nMAssay Description:Inhibition of inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed