BDBM50113050 CHEMBL31065::N-{5-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidine-1-carbonyl]-benzofuran-2-ylmethyl}-2-(2-oxo-5-trifluoromethyl-2H-pyridin-1-yl)-acetamide

SMILES FC(F)(F)c1ccc(=O)n(CC(=O)NCc2cc3cc(ccc3o2)C(=O)N2CCC(CC2)N2C(=O)OCc3ccccc23)c1

InChI Key InChIKey=IPCCGVSSQPPAAN-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50113050   

TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50113050(CHEMBL31065 | N-{5-[4-(2-Oxo-4H-benzo[d][1,3]oxazi...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-oxytocin from human oxytocin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50113050(CHEMBL31065 | N-{5-[4-(2-Oxo-4H-benzo[d][1,3]oxazi...)
Affinity DataKi:  2nMAssay Description:Displacement of 3[H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50113050(CHEMBL31065 | N-{5-[4-(2-Oxo-4H-benzo[d][1,3]oxazi...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-oxytocin from oxytocin receptor in human uterus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50113050(CHEMBL31065 | N-{5-[4-(2-Oxo-4H-benzo[d][1,3]oxazi...)
Affinity DataKi:  1.26E+3nMAssay Description:Compound was tested for its ability to displace vasopressin from human Vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50113050(CHEMBL31065 | N-{5-[4-(2-Oxo-4H-benzo[d][1,3]oxazi...)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Drugmoldesign

Curated by ChEMBL
LigandPNGBDBM50113050(CHEMBL31065 | N-{5-[4-(2-Oxo-4H-benzo[d][1,3]oxazi...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]-vasopressin from vasopressin V2 receptor in human kidney tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50113050(CHEMBL31065 | N-{5-[4-(2-Oxo-4H-benzo[d][1,3]oxazi...)
Affinity DataIC50:  3.04E+3nMAssay Description:Compound was tested for displacement of 3[H] oxytocin from rat OT receptor (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed