BDBM50113317 Bis[4-Amino-5-hydroxy-6-(2-methoxy-phenylazo)-naphthalene-1,3-disulfonic acid](Chicago Sky Blue)::CHEMBL311909

SMILES COc1cc(ccc1N=Nc1ccc2c(cc(c(N)c2c1O)S(O)(=O)=O)S(O)(=O)=O)-c1ccc(N=Nc2ccc3c(cc(c(N)c3c2O)S(O)(=O)=O)S(O)(=O)=O)c(OC)c1

InChI Key InChIKey=OHMJKMNGYYWCHB-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113317   

TargetVesicular glutamate transporter 3(Rattus norvegicus)
The University Of Montana

Curated by ChEMBL
LigandPNGBDBM50113317(Bis[4-Amino-5-hydroxy-6-(2-methoxy-phenylazo)-naph...)
Affinity DataKi:  190nMAssay Description:Evaluated for competitive inhibition against Vesicular glutamate transporter (VGLUT), and Ki value was reported.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50113317(Bis[4-Amino-5-hydroxy-6-(2-methoxy-phenylazo)-naph...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of human NTCP mediated TCA uptake in U2OS expresseing HA-tagged NTCP cells preincubated for 10 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50113317(Bis[4-Amino-5-hydroxy-6-(2-methoxy-phenylazo)-naph...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of preS1-peptide binding to human HA-tagged NTCP in U2OS expresseing NTCP in incubated for 24 hrs using Myrcludex B as substrate by compet...More data for this Ligand-Target Pair
In DepthDetails PubMed