BDBM50118096 2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bis(4,1-phenylene))bis(2-oxoacetic acid)::CHEMBL129681::{4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-oxo-acetic acid

SMILES OC(=O)C(=O)c1ccc(OCc2ccc(COc3ccc(cc3)C(=O)C(O)=O)cc2)cc1

InChI Key InChIKey=HNHFGJRWYYEILT-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50118096   

TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  700nMAssay Description:Concentration required for 50% Inhibition of activity against Yersinia Protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  2.50E+5nMAssay Description:Concentration required for 50% Inhibition of activity against Protein-tyrosine phosphatase LarMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  2.70E+3nMAssay Description:Concentration required for 50% Inhibition of activity against Protein Tyrosine Phosphatases 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  5.73E+3nMAssay Description:Inhibition of PTP1B (unknown origin) by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  5.35E+3nMAssay Description:Inhibition of TCPTP (unknown origin) by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  5.73E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  6.24E+3nMAssay Description:Inhibition of GST-tagged human TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  6.24E+3nMAssay Description:Inhibition of TCPTP by para-nitrophenyl phosphate release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  3.89E+3nMAssay Description:Inhibition of PTP1B by para-nitrophenyl phosphate release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  5.73E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096(2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bi...)
Affinity DataIC50:  3.89E+3nMAssay Description:Inhibition of GST-tagged human PTP 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed