BDBM50118780 3-(carboxyformamido)-5-(3-nitrophenyl)thiophene-2-carboxylic acid::5-(3-Nitro-phenyl)-3-(oxalyl-amino)-thiophene-2-carboxylic acid::CHEMBL141481

SMILES OC(=O)C(=O)Nc1cc(sc1C(O)=O)-c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=DSXQEBLHPSPYIO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118780   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118780(3-(carboxyformamido)-5-(3-nitrophenyl)thiophene-2-...)
Affinity DataKi:  4.68E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118780(3-(carboxyformamido)-5-(3-nitrophenyl)thiophene-2-...)
Affinity DataKi:  4.69E+3nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118780(3-(carboxyformamido)-5-(3-nitrophenyl)thiophene-2-...)
Affinity DataKi:  4.70E+3nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118780(3-(carboxyformamido)-5-(3-nitrophenyl)thiophene-2-...)
Affinity DataKi:  1.65E+5nMpH: 5.5Assay Description:Inhibitory effect against protein-tyrosine phosphatase Lar, using p-nitrophenyl phosphate as substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118780(3-(carboxyformamido)-5-(3-nitrophenyl)thiophene-2-...)
Affinity DataKi:  7.00E+5nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed