BDBM50118824 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid thiophen-3-ylamide; hydrochloride::CHEMBL343521::CHEMBL553824

SMILES: COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccsc3)c2cc1OC

InChI Key: InChIKey=SACBQFMSEKIABM-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Human)	BDBM50118824 (CHEMBL343521 | CHEMBL553824 | 4-(6,7-Dimethoxy-qui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50118824 (CHEMBL343521 | CHEMBL553824 | 4-(6,7-Dimethoxy-qui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50118824 (CHEMBL343521 | CHEMBL553824 | 4-(6,7-Dimethoxy-qui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50118824 (CHEMBL343521 | CHEMBL553824 | 4-(6,7-Dimethoxy-qui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50118824 (CHEMBL343521 | CHEMBL553824 | 4-(6,7-Dimethoxy-qui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair