BDBM50119255 2-[2-(2,3-Diphenyl-propylamino)-acetylamino]-4-methyl-pentanoic acid (2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL101622

SMILES CC(C)CC(NC(=O)CNCC(Cc1ccccc1)c1ccccc1)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=JMCSMHDKXZIFQR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119255   

TargetCaspase-3(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119255(2-[2-(2,3-Diphenyl-propylamino)-acetylamino]-4-met...)
Affinity DataIC50: 320nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119255(2-[2-(2,3-Diphenyl-propylamino)-acetylamino]-4-met...)
Affinity DataIC50: 589nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119255(2-[2-(2,3-Diphenyl-propylamino)-acetylamino]-4-met...)
Affinity DataIC50: 790nMAssay Description:Inhibition of Caspase-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119255(2-[2-(2,3-Diphenyl-propylamino)-acetylamino]-4-met...)
Affinity DataIC50: 990nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119255(2-[2-(2,3-Diphenyl-propylamino)-acetylamino]-4-met...)
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of Caspase-7 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed