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BDBM50121711 CHEMBL169895::DAMPAQ

SMILES: CCc1cc(NS(=O)(=O)c2ccc3c(cccc3c2)N(C)C)cc(CC)c1-n1c(=O)n(C)c2ccccc2c1=O

InChI Key: InChIKey=TXQLSRMMWOKDRH-UHFFFAOYSA-N

Data: 1 IC50

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Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121711   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Puromycin-sensitive aminopeptidase


(Homo sapiens (Human))
BDBM50121711
PNG
(CHEMBL169895 | DAMPAQ)
Show SMILES CCc1cc(NS(=O)(=O)c2ccc3c(cccc3c2)N(C)C)cc(CC)c1-n1c(=O)n(C)c2ccccc2c1=O
Show InChI InChI=1S/C31H32N4O4S/c1-6-20-17-23(32-40(38,39)24-15-16-25-22(19-24)11-10-14-27(25)33(3)4)18-21(7-2)29(20)35-30(36)26-12-8-9-13-28(26)34(5)31(35)37/h8-19,32H,6-7H2,1-5H3
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UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4


Bioorg Med Chem Lett 13: 83-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00845-4
BindingDB Entry DOI: 10.7270/Q2RV0N1C
More data for this
Ligand-Target Pair