BDBM50121711 CHEMBL169895::DAMPAQ

SMILES: CCc1cc(NS(=O)(=O)c2ccc3c(cccc3c2)N(C)C)cc(CC)c1-n1c(=O)n(C)c2ccccc2c1=O

InChI Key: InChIKey=TXQLSRMMWOKDRH-UHFFFAOYSA-N

Data: 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121711   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50121711 (CHEMBL169895 | DAMPAQ) Show SMILES CCc1cc(NS(=O)(=O)c2ccc3c(cccc3c2)N(C)C)cc(CC)c1-n1c(=O)n(C)c2ccccc2c1=O Show InChI InChI=1S/C31H32N4O4S/c1-6-20-17-23(32-40(38,39)24-15-16-25-22(19-24)11-10-14-27(25)33(3)4)18-21(7-2)29(20)35-30(36)26-12-8-9-13-28(26)34(5)31(35)37/h8-19,32H,6-7H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Puromycin sensitive aminopeptidase inhibitory activity of the compound was determined by the use of L-Ala AMC with MOLT-4				Bioorg Med Chem Lett 13: 83-6 (2002) Article DOI: 10.1016/s0960-894x(02)00845-4 BindingDB Entry DOI: 10.7270/Q2RV0N1C
					More data for this Ligand-Target Pair