BDBM50122048 1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL346692::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide

SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4[nH]3)CC2)c1Cl

InChI Key InChIKey=WIYPXJWKJSYBKF-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50122048   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity towards Dopamine receptor D3 of rat using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 1 hr by MicroBeta microplate counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]IABN from human D3 receptor expressed in HEK293 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-IABN from D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK293 cell membranes by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  103nMAssay Description:Displacement of [125I]IABN from human D2L receptor expressed in HEK293 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cells after 1 hr by MicroBeta microplate counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  103nMAssay Description:Displacement of [125I]-IABN from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  135nMAssay Description:Binding affinity towards human Dopamine receptor D2 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  760nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi: >800nMAssay Description:Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50122048(1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-ph...)
Affinity DataKi:  1.66E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed