BDBM50122999 3-(2-Methoxy-pyrimidin-4-yl)-2-phenyl-imidazo[1,2-a]pyrimidin-7-ylamine::CHEMBL115509

SMILES COc1nccc(n1)-c1c(nc2nc(N)ccn12)-c1ccccc1

InChI Key InChIKey=YGBTVRUWFYRCNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122999   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50122999(3-(2-Methoxy-pyrimidin-4-yl)-2-phenyl-imidazo[1,2-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50122999(3-(2-Methoxy-pyrimidin-4-yl)-2-phenyl-imidazo[1,2-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed