BDBM50127395 3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL297507

SMILES CCc1ccc(cc1I)[C@H]1C[C@H]2CCC(N2)C1C(=O)OC

InChI Key InChIKey=BSMPOYNWUIFFDN-KCNJBTMXSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50127395   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127395(3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]octa...)
Affinity DataKi:  0.0630nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127395(3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]octa...)
Affinity DataKi:  89nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127395(3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50:  329nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127395(3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50:  148nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127395(3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed