BDBM50127760 2-[4-(4-Ethoxy-phenyl)-6-methyl-pyrimidin-2-yloxy]-3,3-diphenyl-butyric acid::CHEMBL46311

SMILES CCOc1ccc(cc1)-c1cc(C)nc(OC(C(O)=O)C(C)(c2ccccc2)c2ccccc2)n1

InChI Key InChIKey=KWXXXHXCVVFIMQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127760   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50127760(2-[4-(4-Ethoxy-phenyl)-6-methyl-pyrimidin-2-yloxy]...)
Affinity DataKi:  2nMAssay Description:Antagonist activity of the compound against human ETA receptor using CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50127760(2-[4-(4-Ethoxy-phenyl)-6-methyl-pyrimidin-2-yloxy]...)
Affinity DataKi:  344nMAssay Description:Antagonist activity of the compound against human Endothelin B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed