BDBM50130465 CHEMBL105955::N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-butyramide

SMILES CCCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1

InChI Key InChIKey=JJDBTUIYFOHXHH-UHFFFAOYSA-N

Data  1 KI  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130465   

Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50130465(CHEMBL105955 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CCCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
Show InChI InChI=1S/C17H24N4O/c1-3-4-16(22)19-15-6-5-14-17(20-15)13(11-18-14)12-7-9-21(2)10-8-12/h5-6,11-12,18H,3-4,7-10H2,1-2H3,(H,19,20,22)
Affinity DataKi:  6.90nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50130465(CHEMBL105955 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CCCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
Show InChI InChI=1S/C17H24N4O/c1-3-4-16(22)19-15-6-5-14-17(20-15)13(11-18-14)12-7-9-21(2)10-8-12/h5-6,11-12,18H,3-4,7-10H2,1-2H3,(H,19,20,22)
Affinity DataEC50:  13nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair