BDBM50131053 10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::10-Methoxylrutaecarpine::CHEMBL85826::cid_378227

SMILES: COc1ccc2[nH]c-3c(CCn4c-3nc3ccccc3c4=O)c2c1

InChI Key: InChIKey=JNHSRGXMKPJTEV-UHFFFAOYSA-N

Data: 6 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50131053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Signal transducer and activator of transcription 3 [702-738,740-752] (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.57E+4	n/a	n/a	n/a	n/a
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Transcription factor p65 (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	185	n/a	n/a	n/a	n/a
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Signal transducer and activator of transcription 1-alpha/beta (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<2.83	n/a	n/a	n/a	n/a
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Signal transducer and activator of transcription 3 [702-738,740-752] (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.86E+4	n/a	n/a	n/a	n/a
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Cytochrome P450 1A1 (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1B1 (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1B1 (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1A1 (Human)	BDBM50131053 (10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair