BDBM50131679 CHEMBL3628211::p-Hydroxyphenylethyl p-coumarate (17)

SMILES Oc1ccc(CCOC(=O)\C=C\c2ccc(O)cc2)cc1

InChI Key InChIKey=ZCFLGZLKECDZFW-BJMVGYQFSA-N

Data  13 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50131679   

TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  370nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  510nMAssay Description:Inhibition of human carbonic anhydrase 6 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  620nMAssay Description:Inhibition of human carbonic anhydrase 5B preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  710nMAssay Description:Inhibition of human catalytic domain of carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  730nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  850nMAssay Description:Inhibition of human carbonic anhydrase 5A preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  3.87E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Seoul National University

LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  7.49E+3nM ΔG°:  -7.27kcal/mole IC50:  3.48E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  9.67E+3nMAssay Description:Inhibition of human carbonic anhydrase 4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  1.27E+4nMAssay Description:Inhibition of human catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi:  1.39E+4nMAssay Description:Inhibition of mouse carbonic anhydrase 13 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 3 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50131679(CHEMBL3628211 | p-Hydroxyphenylethyl p-coumarate (...)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged cytoplasmic c-MET kinase domain (956 to 1390 residues) phosphorylation expressed in baculovirus...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed