BDBM50131959 2-(4-Benzothiazol-2-yl-phenylsulfanyl)-5-(4-oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-cyclopentanecarboxylic acid::CHEMBL125138

SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1nc2ccccc2s1

InChI Key InChIKey=UROHLDAMBMAOKL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50131959   

TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131959(2-(4-Benzothiazol-2-yl-phenylsulfanyl)-5-(4-oxo-4H...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131959(2-(4-Benzothiazol-2-yl-phenylsulfanyl)-5-(4-oxo-4H...)
Affinity DataIC50: 417nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131959(2-(4-Benzothiazol-2-yl-phenylsulfanyl)-5-(4-oxo-4H...)
Affinity DataIC50: 661nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131959(2-(4-Benzothiazol-2-yl-phenylsulfanyl)-5-(4-oxo-4H...)
Affinity DataIC50: 829nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131959(2-(4-Benzothiazol-2-yl-phenylsulfanyl)-5-(4-oxo-4H...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed