BDBM50135397 CHEMBL340773::[4-Phenyl-5-(2,4,6-trimethyl-phenylcarbamoyl)-thiazol-2-yl]-carbamic acid tert-butyl ester

SMILES Cc1cc(C)c(NC(=O)c2sc(NC(=O)OC(C)(C)C)nc2-c2ccccc2)c(C)c1

InChI Key InChIKey=CJSMRSKBJZEIAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135397   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135397([4-Phenyl-5-(2,4,6-trimethyl-phenylcarbamoyl)-thia...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CD3/CD28 T-cell proliferation assay in PBL (peripheral blood lymphocytes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed