BDBM501373 5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N- [(2-methyltetrazol-5-yl)methyl]pyrazolo[4,3- b]pyridin-7-amine::US11026923, Example 8

SMILES CCOc1ncccc1-c1cc(NCc2nnn(C)n2)c(NC(C)C)c(n1)C(C)=N

InChI Key InChIKey=HRQDHIDSKXKALG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 501373   

LigandPNGBDBM501373(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N- [(2...)
Affinity DataIC50:  2.90nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501373(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N- [(2...)
Affinity DataIC50:  8.90nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501373(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N- [(2...)
Affinity DataIC50:  0.340nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent