BDBM50139955 3-[4-((Z)-2-Iodo-vinyl)-phenyl]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL275212::methyl 3-{4-[(Z)-2-iodovinyl]phenyl}-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate

SMILES COC(=O)C1C2CCC(CC1c1ccc(\C=C/I)cc1)N2C

InChI Key InChIKey=ABXUYGWOEIXKBD-KTKRTIGZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139955   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139955(3-[4-((Z)-2-Iodo-vinyl)-phenyl]-8-methyl-8-aza-bic...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139955(3-[4-((Z)-2-Iodo-vinyl)-phenyl]-8-methyl-8-aza-bic...)
Affinity DataKi:  22nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139955(3-[4-((Z)-2-Iodo-vinyl)-phenyl]-8-methyl-8-aza-bic...)
Affinity DataKi:  450nMAssay Description:In vitro binding affinity of the compound was determined against human norepinephrin transporter in human embryonic kidney cell line by using [125I]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed