BDBM50140317 (R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phenyl]-propionic acid::CHEMBL417452
SMILES C[C@@H](C(O)=O)c1ccc(C[C@H]2CCC[C@@H]2O)cc1
InChI Key InChIKey=SHAHPWSYJFYMRX-HONMWMINSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50140317
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibitory potency against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against recombinant human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair