BDBM50140317 (R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phenyl]-propionic acid::CHEMBL417452

SMILES C[C@@H](C(O)=O)c1ccc(C[C@H]2CCC[C@@H]2O)cc1

InChI Key InChIKey=SHAHPWSYJFYMRX-HONMWMINSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50140317   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140317((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibitory potency against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140317((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140317((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against recombinant human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50140317((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50140317((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed