BDBM50143947 4-Fluoro-N-{2-[4-(2-hydroxy-3-phenoxy-propyl)-piperazin-1-yl]-2-phenyl-ethyl}-benzamide::CHEMBL60271

SMILES OC(COc1ccccc1)CN1CCN(CC1)C(CNC(=O)c1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=IVZIIWNEAMMPEW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143947   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50143947(4-Fluoro-N-{2-[4-(2-hydroxy-3-phenoxy-propyl)-pipe...)
Affinity DataKi:  7.00E+3nMAssay Description:Predictive competitive inhibition of cytochrome P450 2D6 was determined in silicoMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Arqule

Curated by ChEMBL
LigandPNGBDBM50143947(4-Fluoro-N-{2-[4-(2-hydroxy-3-phenoxy-propyl)-pipe...)
Affinity DataIC50:  363nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed