BDBM50144806 7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione::7-chloro-3-hydroxyquinazoline-2,4-dione::CHEMBL80594

SMILES On1c(=O)[nH]c2cc(Cl)ccc2c1=O

InChI Key InChIKey=CRTPJJNXJPKDEZ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144806   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50144806(7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione | 7-ch...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50144806(7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione | 7-ch...)
Affinity DataKi:  70nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50144806(7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione | 7-ch...)
Affinity DataKi:  240nMAssay Description:Ability of compound to displace [3H]-glycine from N-methyl-D-aspartate glutamate receptor 1 from in cerebral cortex synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50144806(7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione | 7-ch...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50144806(7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione | 7-ch...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed