BDBM50146462 (2E)-3-(2-hydroxyphenyl)-2-propenoic acid::(2E)-3-(2-hydroxyphenyl)prop-2-enoic acid::(2E)-3-(2-hydroxyphenyl)prop-2-enoic acid (7)::(E)-2-hydroxycinnamic acid::(E)-3-(2-hydroxyphenyl)-2-propenoic acid::(E)-o-hydroxycinnamic acid::CHEMBL52564::o-Hydroxycinnamic acid (o-HCA)::o-hydroxy-trans-cinnamic acid::trans-2-coumaric acid::trans-o-hydroxycinnamic acid

SMILES: c1ccc(c(c1)\C=C\C(=O)O)O

InChI Key: InChIKey=PMOWTIHVNWZYFI-UHFFFAOYSA-N

Data: 23 KI  6 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50146462   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 [1-321] (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	7.5	37
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Dihydroorotate dehydrogenase (fumarate) (Leishmania major)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (fumarate) (Leishmania major)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyphenol oxidase 2 (White button mushroom)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear factor NF-kappa-B p105 subunit (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Siderophore-binding protein (Mycobacterium tuberculosis)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		120	-9.43	n/a	n/a	n/a	n/a	n/a	7.5	25
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Beta-carbonic anhydrase 1 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.25E+3	-7.70	n/a	n/a	n/a	n/a	n/a	7.5	25
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Carbonic anhydrase 1 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		4.17E+3	-7.33	n/a	n/a	n/a	n/a	n/a	7.5	25
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Carbonic anhydrase 2 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5B, mitochondrial (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.78E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 3 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5A, mitochondrial (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 6 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 13 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 14 (Human)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 15 (Mouse)	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)prop-2-enoic acid | trans-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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