BDBM50146668 (S)-((S)-1-Methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(pyrimidin-2-yloxy)-acetic acid::CHEMBL92612

SMILES CN1c2ccccc2[C@](NCC1=O)([C@H](Oc1ncccn1)C(O)=O)c1ccccc1

InChI Key InChIKey=AJPNEAQSWFQACP-KNQAVFIVSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146668   

TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50146668((S)-((S)-1-Methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydr...)
Show SMILES CN1c2ccccc2[C@](NCC1=O)([C@H](Oc1ncccn1)C(O)=O)c1ccccc1
Show InChI InChI=1S/C22H20N4O4/c1-26-17-11-6-5-10-16(17)22(25-14-18(26)27,15-8-3-2-4-9-15)19(20(28)29)30-21-23-12-7-13-24-21/h2-13,19,25H,14H2,1H3,(H,28,29)/t19-,22+/m1/s1
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity towards human recombinant Endothelin B receptor expressed in chinese hamster ovary (CHO) cells determined using [125I]-ET-1 as ra...More data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50146668((S)-((S)-1-Methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydr...)
Show SMILES CN1c2ccccc2[C@](NCC1=O)([C@H](Oc1ncccn1)C(O)=O)c1ccccc1
Show InChI InChI=1S/C22H20N4O4/c1-26-17-11-6-5-10-16(17)22(25-14-18(26)27,15-8-3-2-4-9-15)19(20(28)29)30-21-23-12-7-13-24-21/h2-13,19,25H,14H2,1H3,(H,28,29)/t19-,22+/m1/s1
Affinity DataIC50: 1.57E+3nMAssay Description:Antagonist activity towards human recombinant Endothelin A receptor expressed in chinese hamster ovary (CHO) cells determined using [125I]-ET-1 as ra...More data for this Ligand-Target Pair