BDBM50147581 1-tridecanecarboxylic acid::14:0::CH3-[CH2]12-COOH::CHEMBL111077::Myristinsaeure::acide tetradecanoique::myristic acid::n-Tetradecan-1-oic acid::n-Tetradecoic acid::n-tetradecanoic acid::tetradecoic acid

SMILES CCCCCCCCCCCCCC(O)=O

InChI Key InChIKey=TUNFSRHWOTWDNC-UHFFFAOYSA-N

Data  1 KI  7 IC50  4 EC50

PDB links: 373 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50147581   

TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataKi:  2.64E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Bos taurus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
University Of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of TLR2 agonist Pam3Cys-Ser-(Lys)4-OH-mediated IL8 secretion in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50:  5.40E+3nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataEC50:  1.30E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50:  2.40E+4nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataEC50:  1.14E+4nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataEC50:  7.01E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataEC50:  1.44E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO cell membranes assessed as induction of [35S]GTPgammaS incorporation incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50:  2.10E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair