BDBM50148270 CHEMBL3739699

SMILES CCCOc1ccn2c(cc(-c3ccccc3S(C)(=O)=O)c2c1)C(C)=O

InChI Key InChIKey=KHWCPNJRJCNVRI-UHFFFAOYSA-N

Data  5 IC50  7 Kd

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50148270   

TargetBromodomain adjacent to zinc finger domain protein 2A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  3.16E+3nMAssay Description:Binding affinity to BAZ2A in human HUT78 cell extract by chemoproteomic competition binding assayMore data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  3.16E+3nMAssay Description:Binding affinity to BAZ2B in human HUT78 cell extract by chemoproteomic competition binding assayMore data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  60nMAssay Description:Binding affinity to biotinylated C-terminal Avi/His-TEV-tagged BAZ2B (unknown origin) expressed in Escherichia coli by Biolayer Interferometric analy...More data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2A expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataIC50:  430nMAssay Description:Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...More data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataIC50:  360nMAssay Description:Competitive binding affinity to His-tagged BRAZ2B (unknown origin) expressed in Escherichia coli BL21(DE3) cells by AlphaScreen assay in presence of ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of BRD9 (unknown origin) incubated for 30 mins in presence of biotinylated peptide by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain adjacent to zinc finger domain protein 2A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  257nMAssay Description:Binding affinity to recombinant His6-TEV fused human BAZ2A expressed in Escherichia coli by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  136nMAssay Description:Binding affinity to recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to biotinylated C-terminal Avi/His-TEV-fused BRD9 (unknown origin) expressed in Escherichia coli by isothermal titration calorimetri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  3.19E+3nMAssay Description:Binding affinity to biotinylated C-terminal Avi/His-TEV-fused TAF1L bromodomain-2 (unknown origin) expressed in Escherichia coli by isothermal titrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) incubated for 30 mins in presence of biotinylated peptide by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed